
Physical activity interventions that specifically target female adolescents' physical activity participation are needed. However, concerning the health-related quality of life, girls had higher mean scores in physical component summary and mental component summary than boys. More girls were less active than the boys. In addition, boys had a higher mean score of total physical activity (MET-min/week) than the girls.

The findings showed a significant positive association among gender, class of study, parental type, perceived susceptibility to coronavirus disease 2019, and physical activity domains, levels, and health-related quality of life. Female adolescents had higher mean scores in physical component summary ( M = 83.03 SD = 27.36) and mental component summary ( M = 51.19 SD = 8.69) than the male adolescents, physical component summary ( M = 69.0 SD = 21.65) and mental component summary ( M = 46.15 SD = 10.71). The mental health component of health-related quality of life showed that adolescents had poor mental health status. The mean overall score of health-related quality of life was 78.30 ( SD = 16.43). The mean score of total physical activity (MET-min/week) was 1651.3 ( SD = 842.18). Descriptive statistics, Chi-square test, independent-samples t-test, univariate ANOVA, and multiple linear regressions were conducted using SPSS version 25. The Demographic Profile Form, International Physical Activity Questionnaire, Short Form-36 Health Survey, and Perceived Susceptibility to coronavirus disease 2019 Infection Questionnaire were used for data collection. The students were randomly selected to participate in the cross-sectional study between November 2020 and April 2021. The sample consisted of 430 students in public secondary schools in Nsukka, Enugu State. This study assessed the physical activity domains, levels, and health-related quality of life in Nigerian adolescents during the coronavirus disease 2019 pandemic.

However, the evidence is unclear in Nigerian adolescents. Such measures might have negatively impacted adolescents' participation in physical activity and health-related quality of life. The coronavirus disease 2019 pandemic spurred unprecedented public health measures to curb its spread.
